Dr. Mignonne C Guy

Dr. Mignonne Guy

Assistant Professor
(804) 828-7038

Education:  Ph.D. (2009), University of Arizona


Dr. Guy’s research focuses on social, behavioral, biological, and environmental determinants that contribute to health disparities among racial/ethnic minority and other marginalized populations. Most recently, her research examines bio behavioral and environmental factors associated with tobacco-related disparities among young adults/adult populations. She has a strong interest in the complex interplay between distal structural and proximal factors and how they shape the health behaviors and outcomes in African Americans.

She is a co-investigator in the Virginia Commonwealth University Center for the Study of Tobacco Products, where she and her colleagues investigate the diversity of use behaviors of emerging tobacco products and how these behaviors are transmitted through social media as well as the role of flavorants in the initiation and maintenance of using tobacco products. As principal investigator, she recently completed a study funded by the Truth Initiative that examined culturally targeted flavored little cigar and cigarillo smoking prevention media for Latino and African American youth.  Additionally, she is a faculty mentor in the Examining Development, Genes, and Environment lab (EDGE) where she co-mentors and collaborates with postdoctoral fellows to investigate the role of genetic and environmental influences on alcohol use among African Americans.

Her work utilizes mixed-methods approaches that she applies to transdisciplinary collaborations. 

Broad research interests:

Health inequalities; Cancer prevention and control; Cancer risk behaviors; Gene-environment interactions; Racial/ethnic minority representation in genetic research. 

Substantive research interests:

Substance use: conventional and emerging tobacco products, alcohol; Prostate cancer


Selected Publications:

Tobacco Use 

Guy, MC, Helt, J, Palafox, S, Green, K, Soule, E,  Maloney, S, Eissenberg, T, Fagan, P. Orthodox and unorthodox uses of electronic cigarettes: A surveillance of YouTube video content. Nicotine Tob Res. 2018 Jun 28. doi: 10.1093/ntr/nty132. [Epub ahead of print] PMID: 29961828  

Cooper, M, Pacek, L, Guy, M, Barrington-Trimis, J, Simon, P, Stanton, C, Kong, G. Hookah use among U.S. youth: A systematic review of the literature from 2009-2017. Nicotine Tob Res. 2018 Jun 28. doi: 10.1093/ntr/nty135. [Epub ahead of print] PMID: 29961895 

Soule EK, Maloney SF, Guy MC, Eissenberg T, Fagan P. User-identified electronic cigarette behavioral strategies and device characteristics for cigarette smoking reduction. Addict Behav. 2018 Apr; 79: 93-101. doi: 10.116/j.addbeh.2017.12.010. Epub 2017 Dec 8. 

Fagan P, Pokhrel P, Herzog TA, Moolchan ET, Cassel KD, Franke AA, Li X, Pagano I, Trinidad DR, Sakuma KK, Sterling K, Jorgensen D, Lynch T, Kawamoto C, Guy MC, Lagua I, Hanes S, Alexander LA, Clanton MS, Graham-Tutt C, Eissenberg T; Addictive Carcinogens Workgroup. Sugar and Aldehyde Content in Flavored Electronic Cigarette Liquids. Nicotine Tob Res. 2017 Nov 22. doi: 10.1093/ntr/ntx234. [Epub ahead of print]. 

Fagan P,Pokhrel P, Herzog TA, Guy MC, Sakuma KK, Trinidad DR, Cassel K, Jorgensen D, Lynch T, Felicitas-Perkins JQ, Palafox S, Hamamura F, Maloney S, Degree K, Sterling K, Moolchan E, Clanton MS, Eissenberg T; Addictive Carcinogens Workgroup. Warning Statements and Safety Practices among Manufacturers and Distributors of Electronic Cigarette Liquids in the United States. Nicotine Tob Res. 2017 May 18. doi: 10.1093/ntr/ntx101. [Epub ahead of print]. 

Soule EK, Lopez AA, Guy MC, Cobb CO. Reasons for using flavored liquids among electronic cigarette users: A concept mapping study. Drug Alcohol Depend. 2016 Sept; 166: 167-76.

Nasim A, Guy MC, Soule EK, Cobb CO, Blank MD, Eissenberg T. Characteristics and patterns of Black & Mild use among African American smokers. Nicotine Tob Res. 2016 May;18(5):842-9.  

Michael SS, Seltzer RGN, Guy MC. Association between quitline facility type and subsequent client contact. Health Behavior and Policy Review. 2014; 2(3): 225-231. 

Goldade K, Guo H, Des Jarlais D, Connett JE, Whembola GL, Owen G, Guy MC, Okuyemi K. Homeless former smokers’ interest in helping homeless current smokers quit.  American Journal of Health Promotion. 2012; 27(2): 90-3.

Guy MC, Seltzer RGN, Cameron M, Pugmire J, Michael SS, Leischow SJ. The Arizona Smokers’ Helpline: Examining the relationship between smokers’ mode of entry into quitlines and treatment outcomes.  American Journal of Health Behavior. 2012; 36(1): 3-11.  


Cancer Prevention and Control

Khera N, Chang YH, Slack J, Fauble V, Leis JF, Noel P, Sproat L, Palmer J, Adams R, Fitch T, Northfelt D, Guy MC, Tilburt J, Mikhael J. Impact of race and ethnicity on outcomes and health care utilization after allogeneic hematopoietic cell transplantation. Leukemia and Lymphoma. 2014; 1-6. 

Murphy AB, Akereyeni F, Nyame YA, Guy MC, Walker K, Allen D, Kittles RA, Ahaghotu CA. Smoking and risk of prostate cancer in a multi-ethnic sample.  The Prostate. 2013; 73(14): 1518-1528.


Alcohol and Other Substance Use

Su, J, Kuo, S, Meyers, JL, Guy, MC, Dick, DM. Examining interactions between genetic risk for alcohol problems, peer deviance, and interpersonal traumatic events on trajectories of alcohol use disorder symptoms among African American college students. Development and Psychopathology. (In press).

Su J, Kuo, S, Aliev, F, Guy, MC, Derlan, CL, Edenberg, HJ, Nurnberger, JI, Kramer, JR, Bucholz, KK, Salvatore, JE, Dick, DM. Influence of parental alcohol dependence symptoms and parenting on adolescent risky drinking and conduct problems: A family systems perspective. Alcoholism: Clinical and Experimental Research. (In press).


Invited Special Issue Articles

Dick, DM, Barr P, Guy M, Nasim A, Scott D. Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications. Am J Addict. 2017 Aug; 26(5):486-493.doi: 10.1111/ajad.12495. Epub 2017 Feb 27. Invited Review.

Baezconde-Garbanati L, Guy MC, Soto C. The use of quitlines among priority populations in the U.S.: Lessons from the scientific evidence. North American Quitline Consortium. 2011.


Recent Courses:

Interdisciplinary Research Methods (Undergraduate)

Black Health Matters: Social Determinants of Health in the African American Community (Undergraduate)

Senior Capstone (Undergraduate)